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Altered expression of cell cycle and apoptotic proteins in chronic hepatitis C virus infection

Saira Sarfraz1, Saeed Hamid2*, Anwar Siddiqui1, Snawar Hussain3, Shahid Pervez4 and Graeme Alexander5

Author Affiliations

1 Department of Biological and Biomedical Sciences, Aga Khan University, Karachi, Pakistan

2 Department of Medicine, Aga Khan University, Karachi, Pakistan

3 Department of Microbiology and Immunology, Loyola University Medical Center, Maywood, Illinios, USA

4 Department of Histopathology, Aga Khan University Hospital, Karachi, Pakistan

5 Department of Medicine, Addenbrooke's Hospital, University of Cambridge, Cambridge, CB2 2QQ, UK

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BMC Microbiology 2008, 8:133  doi:10.1186/1471-2180-8-133

Published: 5 August 2008

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Additional file 1:

Expression of Mcm-2 and G1-S phase Cyclins. Immunohistochemical staining of biopsy specimens from HCV-infected patients (HCV). Sections were stained using a) anti-Mcm-2, b) anti-Cyclin D and c) anti-Cyclin A. Positive hepatocytes are stained brown (Mayer hematoxylin, magnification 400×).

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