Table 2

Pathogenicity islands in completed genomes of S. aureus

ISLAND

VIRULENCE GENE PRODUCTS

USA300 MRSA

Newman

NCTC 8325

COL

MW2

MSSA 476

N315

Mu50

JH1

JH9

RF122

MRSA 252


SaPI1

TSST, SEK, SEL, Ear

-

-

-

-

-

-

-

-

-

-

-

-

SaPI2

TSST, exfoliatin

-

-

-

-

-

-

-

-

-

-

-

-

SaPI3

SEB, SEK, SEQ, Ear

-

-

-

+

-

-

-

-

-

-

-

-

SaPI4

None

-

-

-

-

-

-

-

+

-

-

-

+

SaPI5

SEK, SEQ, Ear

+

-

-

-

+

-

-

-

-

-

-

-

SaPIbov1

TSST, SEK, SEL

-

-

-

-

-

-

-

-

-

-

+

-

SaPIbov2

Bap adhesin

-

-

-

-

-

-

-

-

-

-

-

-

SaPIm4

ferrichrome transporter

+

+

+

+

-

-

+

+

+

+

+

-

SaPImw2

Ear, SEC4, SEL2

-

-

-

-

+

-

-

-

-

-

-

-

SaPIn1/m1

TSST, SEL, SEC3

-

-

-

-

-

-

+

+

-

-

-

-

SaPI122

multidrug exporter

-

-

-

-

-

-

-

-

-

-

+

-

SaPI6Δ

None

+

+

+

+

+

+

-

-

-

-

-

-

νSaα

SET exotoxins, lipoproteins

+

+

+

+

+

+

+

+

+

+

+

+

νSaβ

serine proteases, leukotoxin D & E, enterotoxins, epidermin

+a

+a

+a

+a

+a

+a, b

+c

+c

+c

+c

+

+b

νSaγ

SET exotoxins, exfoliatin, alpha-hemolysin

+

+

+

+

+

+

+

+

+

+

+

+


aNo enterotoxin genes

bNo leukotoxin genes

cNo epidermin genes

Highlander et al. BMC Microbiology 2007 7:99   doi:10.1186/1471-2180-7-99

Open Data