Table 4

Designed strategies to enhance 2-acetolactate production, and corresponding predictions for specific growth rates and yields of 2-acetolactate on glucose.

FBA

MOMA


Growth (h-1)

Y (C-mol/C-mol)

Growth (h-1)

Y (C-mol/C-mol)


Reference

0.82

0.31

0.82

0.31

Δldh ΔaldB ΔadhA

0.82

0.32

0.82

0.31

Δldh ΔaldB ΔadhA Δpta

0.56

0.74

0.323

0.34

Δldh ΔaldB ΔadhA Δpta Δfhs

0.56

0.76

0.53

0.75

Δldh ΔaldB ΔadhA Δpta ΔserA

0.56

0.76

0.53

0.74

Δldh ΔaldB ΔadhA Δpta Δzwf

0.38

0.71

0.38

0.75


Oliveira et al. BMC Microbiology 2005 5:39   doi:10.1186/1471-2180-5-39

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