Figure 2.

Phage Replication Assay: Rate of replication of φLH and φLW on CAB1 in LB and in mouse serum. In LB, the growth rates of the K1 phage (φLH, squares connected by the solid line) are similar to those of the non-K1 phage (φLW, solid circles connected by the dashed line) across a range of densities, with both phages growing more rapidly on cells at low density than on cells at high density, near saturation. However, on cells grown in mouse serum, the growth rate is much higher for the K1-specific phage, φLH, (gray triangles) than for the non-K1 specific phage, φLW (gray circles). Growth rate is presented as doublings of phage concentration per hour; standard error bars are given for each black point (on the lines), but most are so short as to be obscured by the point. Each gray point represents one assay in serum.