Figure 1.

HTS assay. Growth of V. cholerae MO10 pG13 strain in 96- (A) and 384-well MTP (B) in the presence of test compounds and controls. (A): 12 A-B: 1% DMSO, 12C-D: 100 μM ciprofloxacin, 12 E-F: no addition of compounds, 12 G-H: sterile medium. (B): 23 A-D and 24 A-D: 1% DMSO, 23 E-H and 24 E-H: 100 μM ciprofloxacin, 23 J-M and 24 J-M: no addition of compounds, 23 M-P and 24 M-P: sterile medium. Upper panels: absorbance at 600 nm; lower panels: fluorescence (485/535 nm). Wells framed in red indicate active compounds.

Sergeev et al. BMC Microbiology 2014 14:49   doi:10.1186/1471-2180-14-49
Download authors' original image