Table 4

O157 proteins up-regulated under anaerobic conditions in uRF, in Experiment II
Protein/Function/Pathway; Name Accession Number Molecular Weight ( kDa)1
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase/Glycolysis/Energy; GpmA GPMA_ECO57 29 kDa
3-oxoacyl-[acyl-carrier-protein] reductase/Fatty acid biosynthesis; FabG Q8X8I5_ECO57 26 kDa
3,4-dihydroxy-2-butanone 4-phosphate synthase, Riboflavin (Vitamin B2) biosynthesis/ Cofactor Bisoynthesis; RibB RIBB_ECO57 23 kDa
30S ribosomal protein S6/Protein Translation; RpsF RS6_ECO57 15 kDa
4-hydroxy-tetrahydrodipicolinate reductase, Leucine synthesis/Amino acid Biosynthesis; DapB DAPB_ECO57 29 kDa
50S ribosomal protein L10/Protein Translation; RplJ RL10_ECO57 18 kDa
50S ribosomal protein L18/Protein Translation; RplR RL18_ECO57 13 kDa
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta/Fatty acid Biosynthesis; AccD ACCD_ECO57 33 kDa
Acriflavine resistance protein A/Multidrug efflux system/Transport; AcrA B5Z3X3_ECO5E 44 kDa
ADP-L-glycero-D-manno-heptose-6-epimerase/LPS core Biosynthesis/Heat induced; HldD HLDD_ECO57 35 kDa
Agmatinase/Polyamine Biosynthesis/Acid Resistance; SpeB SPEB_ECO57 (+1) 34 kDa
AidA-I adhesin-like protein/Adherence; AidA K0AT24_ECO1C 141 kDa
Aminomethyltransferase/Nitrogen, Amino Acid Metabolism; GcvT GCST_ECO57 40 kDa
Argininosuccinate lyase, Arginine synthesis/ Amino Acid Biosynthesis; ArgH ARLY_ECO57 50 kDa
AsmA protein/LPS Biogenesis; AsmA B5YUC4_ECO5E (+5) 69 kDa
Aspartate carbamoyltransferase regulatory chain/Nucleotide Biosynthesis; PyrI PYRI_ECO57 17 kDa
Aspartate--tRNA ligase/Aminoacyl-tRNA Biosynthesis; AspS SYD_ECO57 (+1) 66 kDa
Aspartate-semialdehyde dehydrogenase/Amino acid Biosynthesis; AsD DHAS_ECO57 40 kDa
ATP synthase subunit b/Energy Production; AtpF ATPF_ECO57 17 kDa
ATP-dependent helicase/DNA Replication, Repair; HrpB Q8X904_ECO57 (+1) 91 kDa
ATP-dependent protease subunit/Proteolysis; HslV HSLV_ECO57 19 kDa
Bacterioferritin/Iron storage and Transport; BfR Q8X890_ECO57 18 kDa
Bacteriophage replication gene A protein/Predicted Phage replication; ECH74115_3058 B5YUH3_ECO5E 86 kDa
Beta-D-glucoside glucohydrolase, degradation of small carbon compunds/Biosyntheis of secondary metabolites; BglX Q8X668_ECO57 83 kDa
Bifunctional N-acetylglucosamin-1-phosphate-uridyl transferase/Cell Wall Synthesis; GlmU GLMU_ECO57 (+2) 49 kDa
Bifunctional purine biosynthesis protein/Purine Biosynthesis; PurH PUR9_ECO57 57 kDa
Biofilm regulator/Biofilms, Adherence; BssR BSSR_ECO57 15 kDa
Biosynthetic arginine decarboxylase/Polyamine Biosynthesis, Acid Resistance; SpeA SPEA_ECO57 74 kDa
Biotin carboxyl carrier protein of acetyl-CoA carboxylase/Fatty Acid Biosynthesis; AccB BCCP_ECO57 (+8) 17 kDa
Branched-chain-amino-acid aminotransferase/Amino acid Transport and Metabolism; IlvE ILVE_ECO57 34 kDa
Catabolite repression sensor kinase for PhoB alternative sensor for pho regulon/Global Regulaor; CreC Q8XB07_ECO57 52 kDa
Catalase-peroxidase 1/Prevent Cell, DNA damage/Oxidative Stress; KatG1 KATG1_ECO57 80 kDa
Cell Division protein; ZapB ZAPB_ECO5E (+8) 9 kDa
Cellulose synthase subunit/Biofilms, Adherence; BcsC C8TYF1_ECO10 (+2) 126 kDa
Chromosome partition protein/Cell Division; MukB MUKB_ECO57 (+2) 170 kDa
Curli production assembly/transport subunit/Biofilms, Adherence; CsgG B5YVQ8_ECO5E (+1) 31 kDa
Cyclic pyranopterin monophosphate synthase accessory protein/Cofactor Biosynthesis; MoaC MOAC_ECO57 17 kDa
Cytidylate kinase/Nucleotide Biosynthesis; Cmk KCY_ECO57 25 kDa
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase
Complex/Energy Metabolism; SucB ODO2_ECO57 44 kDa
Dihydroorotase/Nucleotide Biosynthesis; PyrC PYRC_ECO57 39 kDa
DNA helicase/DNA Replication, Transcription; RecB Q8X6M9_ECO57 134 kDa
DNA invertase from prophage CP-933H/DNA Replication; PinH Q8X7L1_ECO57 22 kDa
DNA topoisomerase IV subunit B/DNA Replication; ParE Q8XBQ4_ECO57 70 kDa
DNA-directed RNA polymerase subunit alpha/DNA Transcription; RpoA RPOA_ECO57 37 kDa
DNA-directed RNA polymerase subunit beta/DNA Transcription; RpoB RPOB_ECO57 151 kDa
DNA-directed RNA polymerase subunit omega/DNA Transcription; RpoZ RPOZ_ECO57 10 kDa
Elongation factor P-like protein/Translation, Protein synthesis; YeiP EFPL_ECO57 22 kDa
Evolved beta-D-galactosidase alpha subunit/Degradation of small carbon compounds; EbgA Q8XAM9_ECO57 119 kDa
Ferritin-1/Iron Uptake and Storage; FtnA FTNA_ECO57 19 kDa
Fimbrial usher family protein/Chaperone/Transport; ECH74115_2118 B5Z1W3_ECO5E (+5) 81 kDa
Formate dehydrogenase-O major subunit/Energy Metabolism, Anaerobic Respiration; FdoH Q7A9A6_ECO57 (+1) 113 kDa
Fructose-bisphosphate aldolase, class 1/Glycolysis, Gluconeogensis; FbaB B5YV44_ECO5E (+1) 38 kDa
Galactose-1-phosphate uridylyltransferase/Galactose Metabolism; GalT Q8X943_ECO57 40 kDa
Glucans biosynthesis protein G/Osmotic Adaptation; MdoG OPGG_ECO5E 59 kDa
Glutamate--tRNA ligase/Amino acyl tRNA synthesis; GltX SYE_ECO57 54 kDa
Glutamine synthetase/Amino acid Biosynthesis; GlnA GLNA_ECO57 52 kDa
Glutathione synthetase/Cofactors, carriers Biosynthesis; GshB GSHB_ECO57 35 kDa
Glycerol kinase/Glycerolipid Metabolism; GlpK GLPK_ECO57 56 kDa
Glycine dehydrogenase [decarboxylating]/Amino acid Metabolism; GcvP GCSP_ECO57 104 kDa
GMP synthase [glutamine-hydrolyzing]/Nucleotide Biosynthesis; GuaA GUAA_ECO57 59 kDa
GTPase-activating protein/Transcriptional Activator; YihI YIHI_ECO57 19 kDa
Guanylate kinase/Nucleotide Biosynthesis; GmK KGUA_ECO57 (+2) 24 kDa
Hemin import ATP-binding protein/Transport; HmuV HMUV_ECO57 29 kDa
Histidine--tRNA ligase/Amino acyl tRNA synthesis; HisS SYH_ECO57 47 kDa
HTH-type transcriptional regulator/Maltooligosaccharide Uptake and Metabolism; MalT MALT_ECO57 103 kDa
Hydrogenase-2 large chain/Energy Metabolism/Anaerobic Respiration; HybC MBHM_ECO57 62 kDa
Hydroxyacylglutathione hydrolase/Pyruvate Metabolism; GloB GLO2_ECO57 28 kDa
Inosine-5′-monophosphate dehydrogenase/Nucleotide Biosynthesis; GuaB B5Z0X7_ECO5E 54 kDa
Iron-sulfur cluster insertion protein/Growth using alternate electron acceptors; ErpA ERPA_ECO57 12 kDa
Long-chain fatty acid transport protein/Transport; FadL FADL_ECO57 49 kDa
Low-affinity putrescine importer/Transport; PlaP PLAP_ECO57 50 kDa
LPS-assembly lipoprotein/LPS Biogenesis; LptE LPTE_ECO57 21 kDa
Macrolide export ATP-binding/permease protein/Transport; MacB MACB_ECO57 71 kDa
Major outer membrane lipoprotein/Membrane Integrity; Lpp LPP_ECO57 8 kDa
Mannitol-1-phosphate 5-dehydrogenase/Fructose, Mannose Metabolism; MtlD MTLD_ECO57 41 kDa
Membrane, TerC family/CBS/transporter associated protein/Transport/Tellurium Resistance; TerC B5YUC1_ECO5E (+6) 59 kDa
Methyl-accepting chemotaxis protein III, ribose and galactose sensor receptor/Chemotaxis; Trg C8U899_ECO10 59 kDa
Minor curlin protein/Biofilms, Adherence; CsgB B5YVR3_ECO5E (+1) 17 kDa
Multiple Resistance and pH adaptation protein, antiporter/Transport; Mrp B5YV63_ECO5E (+1) 40 kDa
Multidrug resistance efflux protein/Transport; MdtC C8TU07_ECO26 (+2) 111 kDa
Multiphosphoryl transfer protein/Fructose, Mannose Metabolism; FruB PTFAH_ECO57 40 kDa
N-acetylglucosamine-6-phosphate deacetylase/LPS Biosynthesis; NagA NAGA_ECO57 41 kDa
NADH-quinone oxidoreductase subunit C/D/Electron transfer/Energy Metabolism; NuoC NUOCD_ECO57 (+2) 69 kDa
NifU-like protein/Energy Production, Conversion; NifU NIFU_ECO57 14 kDa
Non-LEE-encoded type III secreted effector; EspX7 C6URC5_ECO5T (+2) 73 kDa
Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein/Transport; OppA B5YYE8_ECO5E 63 kDa
Osmotically-inducible lipoprotein E/Global Regulator; OsmE OSME_ECO57 12 kDa
Outer membrane lipoprotein/Cell Envelope Biogenesis; SlyB SLYB_ECO57 16 kDa
Outer membrane protein, porin, receptor, integrity/Membrane Stability; OmpA B5YT87_ECO5E 38 kDa
Outer membrane protein assembly factor/Membrane Assembly, Antibiotic Resistance; BamA/YaeT BAMA_ECO57 91 kDa
Outer membrane protein assembly factor/Membrane Assembly, Antibiotic Resistance; BamD/YfiO BAMD_ECO57 28 kDa
Outer membrane protein, efflux protein/Transport; TolC B5YR81_ECO5E (+2) 54 kDa
Outer membrane protein W/Outer Membrane Biogenesis; OmpW/YciD Q8XCB6_ECO57 23 kDa
Oxidoreductase subunit/Oxidative Stress; DmsA_YnfF C6UV29_ECO5T (+6) 90 kDa
Penicillin-binding protein activator/Lipid binding/Putative Adhesin; LpoB/YcfM LPOB_ECO57 23 kDa
Peptidase B/Protein Metabolism; PepB PEPB_ECO57 46 kDa
Peptide chain release factor 1/Protein Translation; PrfA RF1_ECO57 41 kDa
Peptidyl-prolyl cis-trans isomerase A/Post-translational Modification; PpiA PPIA_ECO57 20 kDa
Peptidyl-prolyl cis-trans isomerase/Post-translational Modification; FklB B5Z2L4_ECO5E (+2) 22 kDa
Periplasmic binding protein for nickel/Amino acid Transport and Metabolism; NikA Q8X5U3_ECO57 (+1) 59 kDa
Phenylalanine--tRNA ligase alpha subunit/Amino acyl tRNA synthesis; PheS SYFA_ECO57 (+2) 37 kDa
Phenylalanine--tRNA ligase beta subunit/Amino acyl tRNA synthesis; PheT SYFB_ECO57 87 kDa
Poly (A) polymerase I/DNA Transcription; PcnB PCNB_ECO57 (+3) 54 kDa
Proline--tRNA ligase/Amino acyl tRNA synthesis; ProS SYP_ECO57 64 kDa
Protease IgA1, Serine protease/Protection; EspP K0AWD8_ECO1C 146 kDa
Protein elaB/Uncharacterized; ElaB ELAB_ECO57 11 kDa
Protein grpE, prevents aggregation of denatured proteins/ Heat and Hyperosmotic Shock-Related; GrpE C8U980_ECO10 (+2) 22 kDa
Protein translocase subunit/Transport; SecD SECD_ECO57 67 kDa
PTS system, mannose-specific transporter subunit IID/Transport; ManZ B5YQW0_ECO5E (+1) 31 kDa
Putative anaerobic dimethyl sulfoxide reductase chain A; DmsA_YnfE Q7ABM3_ECO57 (+1) 88 kDa
Putative DNA replication factor encoded within cryptic prophage CP-933P/Hypothetical; Z6069 Q8XAD9_ECO57 28 kDa
Putative endopeptidase of prophage CP-933X/Hypothetical; Z1877 Q8X704_ECO57 12 kDa
Putative carboxypeptidase/Hypothetical; YagX Q8X6I4_ECO57 (+1) 91 kDa
Putative lipoprotein induced during stationary phase/Stress Response; YbjP Q8X6N7_ECO57 (+1) 19 kDa
Putative homeobox protein/Regulator; YbgS Q8X948_ECO57 13 kDa
Putative lipoprotein/Membrane protein; LppC B5YUN1_ECO5E 20 kDa
Putative membrane protein, peptidase/Uncharacterized; YibP Q8XDE2_ECO57 47 kDa
Putative multimodular enzyme/Energy Metabolism; Z3719 Q8XBF4_ECO57 82 kDa
Putative pectinesterase, localizes to cellular poles/Membrane protein; YbhC Q8X891_ECO57 46 kDa
Putative replicase/DNA Replication; Z5187 Q8XBZ7_ECO57 37 kDa
Pyridoxine 5′-phosphate synthase/Vitamin B6 (Pyridoxine) synthesis; PdxJ PDXJ_ECO57 26 kDa
Pyruvate dehydrogenase (Dihydrolipoyltransacetylase component)/Energy Metabolism; AceF Q8X966_ECO57 66 kDa
Pyruvate oxidase/Degradation of small carbon compunds; PoxB Q8X6L4_ECO57 62 kDa
RNase E/RNA Degradation; RnE Q8X8J5_ECO57 118 kDa
Serine protease/Protection; DegP B5Z0E1_ECO5E (+1) 49 kDa
Serine endoprotease/Protection; DegQ Q8X9F1_ECO57 47 kDa
Single-stranded DNA-binding protein/DNA Replication; SsB SSB_ECO57 19 kDa
Soluble cytochrome, electron transport/Energy Metabolism; CybC C562_ECO57 (+4) 14 kDa
Spermidine/putrescine import ATP-binding protein/Transport; PotA POTA_ECO57 43 kDa
Stringent starvation protein A, stationary phase induced acid tolerance/Global Regulator; SspA SSPA_ECO57 24 kDa
Stringent starvation protein B, ClpXP protease specificity enhancer/Global Regulator; SspB SSPB_ECO57 18 kDa
Succinate dehydrogenase flavoprotein subunit/Energy Metabolism; SdhA DHSA_ECO57 64 kDa
Tat-linked quality control protein/DNAse activity; TatD Q8X8J6_ECO57 30 kDa
Thiosulfate sulfurtransferase/Anaerobic Respiration, Energy Metabolism; GlpE C8TJL4_ECO26 (+2) 12 kDa
Threonine deaminase (Dehydratase)/Amino acid Biosynthesis; IlvA Q8X467_ECO57 56 kDa
Transcription termination/antitermination protein/Modulates DNA Transcription; NusG NUSG_ECO57 21 kDa
Transcriptional regulatory protein/Envelope Stress Response Protein/Downregulates LEE; CpxR CPXR_ECO57 26 kDa
Transketolase 1, thiamin-binding/Non-oxidative Metabloism; TktA C8TGU9_ECO26 72 kDa
Transketolase 2 isozyme, stationary phase induced/Non-oxidative Metabolism; TktB Q8XBF1_ECO57 (+6) 73 kDa
Translation initiation factor IF-2/Protein Translation; InfB IF2_ECO57 97 kDa
Trigger factor/Cell division; TiG TIG_ECO57 (+1) 48 kDa
Tryptophanase/Tryptophan Metabolism, Indole Production; TnaA TNAA_ECO57 53 kDa
Type II secretion pathway related protein/Transport; EtpE O82884_ECO57 56 kDa
Tyrosine-protein kinase/Downregulates colanic acid production; WzC WZC_ECO57 79 kDa
Uncharacterized protein/Hypothetical; ECs1547 Q8X3G9_ECO57 (+1) 17 kDa
Uncharacterized protein/Hypothetical; ECs2891 Q8X7H8_ECO57 14 kDa
Uncharacterized protein/Hypothetical; ECs2991 Q8X2Z1_ECO57 10 kDa
Putative oxidative stress defense protein/ Oxidative Stress; YggE YGGE_ECO57 27 kDa
Uncharacterized protein/Membrane Protein; YqjD YQJD_ECO57 11 kDa
UPF0042 nucleotide-binding protein/putative ATPase; YhbJ YHBJ_ECO57 32 kDa
UPF0092 membrane protein, translocase/Transport; YajC YAJC_ECO57 12 kDa
UPF0337 protein, putative stress response protein/Osmotic Shock; YjbJ YJBJ_ECO57 8 kDa
UPF0352 protein/Uncharacterized; YejL YEJL_ECO57 8 kDa
Uridylate kinase/Nucleotide Interconversion; PyrH PYRH_ECO57 26 kDa
Valine--tRNA ligase/Amino acyl tRNA Biosynthesis; ValS SYV_ECO57 108 kDa

1kDa, Kilodalton.

Kudva et al.

Kudva et al. BMC Microbiology 2014 14:48   doi:10.1186/1471-2180-14-48

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