Figure 1.

S. aureusinfection of osteoblasts and macrophages.(A) Live intracellular S. aureus and (B) viability of osteoblasts and macrophages at different MOIs (100:1, 500:1, and 1000:1) for 2 h. *p < 0.05 and **p < 0.001 compared to osteoblasts at the same MOI. (C) Live intracellular S. aureus and (D) viability of osteoblasts and macrophages at an MOI of 500:1 for various infection times. **p < 0.001 compared to osteoblasts at the same infection time, &p < 0.01 compared to macrophages at infection times 0 and 0.5 h, ^p < 0.01 compared to osteoblasts at the same infection times, and #p < 0.05 compared to osteoblasts at infection times 0 and 0.5 h. (E) Effect of cytochalasin D on S. aureus internalization in osteoblasts. **p < 0.001 compared to the controls and ^^p < 0.001 compared to 0.5, 1, and 5 μg/mL.

Hamza and Li BMC Microbiology 2014 14:207   doi:10.1186/s12866-014-0207-5
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