The mRNA expression of CXCL8 in THP-1 cells stimulated with wild-type or gingipain mutants of P. gingivalis.CXCL8 transcription following 24 hour treatment of THP-1 cells with (MOI 100) viable ATCC3277 (ATCC), W50, E8, K1A or heat-killed ATCC 33277 (ATCCHK) or W50 (W50HK). Values represent the mean ± SD. Statistically significant differences compared to the negative control. (*p < 0.05; **p < 0.01; ***p < 0.001; n = 3).
Jayaprakash et al. BMC Microbiology 2014 14:193 doi:10.1186/1471-2180-14-193