Table 1

Effects of microbial antigens on lymphocyte growth with or without IL-6 and TGFβ1
Antigen IL-6(-), TGF-β1(-)a IL-6(+), TGF-β1(+)a
0 μg/ml 50 μg/ml 0 μg/ml 1 μg/ml 5 μg/ml 10 μg/ml 50 μg/ml
M. pneumoniae M129 229.6±19.1b 81.9±5.8 101.5±10.9 134.7±15.6c 147.8±6.3c
S. pneumoniae ATCC 33400 18.4±1.2b 110.1±6.3 100.9±12.9 66.8±5.2c 22.3±2.4c
K. pneumonia ATCC 13883 111.7±13.0 6.8±4.2b 100.0±8.1 109.2±4.1c 44.3±1.2c 27.3±1.6c 6.1±0.7c
LPS from E. coli 0127: B8 128.8± 6.1b 86.5±2.7c 89.4±8.1 81.2±5.0c 56.5±7.0c
Zymosan A from S. cerevisiae 197.9±10.2b 104.5±10.1 114.8±9.6c 124.9±4.0c 159.1±5.4

aRelative ratio (%) of viable lymphocyte count with or without IL-6 (20 ng/ml) and TGF-β1 (2 ng/ml) stimulated with M. pneumoniae and other antigens. Relative ratio is the mean ± standard deviation (four or five samples per group) of the number of viable lymphocytes at day 4.

bSignificantly different (p < 0.05) from value for cytokine (−), antigen 0 μg/ml by Student’s t-test.

cSignificantly different (p < 0.05) from value for 20 ng/ml of IL-6 and 2 ng/ml of TGF-β1 (+), antigen 0 μg/ml by Dunnett multiple comparison statistical test.

Kurata et al.

Kurata et al. BMC Microbiology 2014 14:156   doi:10.1186/1471-2180-14-156

Open Data