Time-dependent killing after combined antibiotic treatment. (A) Exponential (solid line) and stationary (dotted line) grown S. suis strain 10 was exposed to a combined antibiotic treatment of 200-fold MIC of penicillin and 4-fold MIC of gentamicin over time. (B) This penicillin/gentamicin combination was also used in a heritability test with exponential (solid line) and stationary (dotted line) grown S. suis in three consecutive cycles. The values are means of two biological replicates plated in triplicate. Error bars indicate the standard deviation.
Willenborg et al. BMC Microbiology 2014 14:120 doi:10.1186/1471-2180-14-120