Table 1

Number of synonymous and non-synonymous changes in DENV serotypes
Category Position 1 Position 2 Position 3 Codons
DENV1-Syn 152 0 1333 1420
DENV1-Nonsyn 128 112 129 244
DENV2-Syn 120 0 1212 1281
DENV2-Nonsyn 109 96 111 211
DENV3-Syn 121 0 1129 1197
DENV3-Nonsyn 102 117 100 218
DENV4-Syn 112 0 1259 1370
DENV4-NonSyn 102 103 109 314

Dengue virus serotypes are listed as DENV1, DENV2, DENV3 and DENV4. Syn: synonymous changes. Nonsyn: non-synonymous changes. Position 1/2/3: 1st, 2nd and 3rd positions of codons. For synonymous changes, the 3rd position substitutions are predominant as expected. However, for non-synonymous changes, all the three positions of codons undergo changes with no significant bias with any specific position. Number of codons associated with non-synonymous (Non-syn) or synonymous (Syn) changes in each serotype are shown in the last column.

Behura and Severson

Behura and Severson BMC Microbiology 2013 13:37   doi:10.1186/1471-2180-13-37

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