Table 3

Cell wall synthesis-related genes that were differentially expressed in the airSR mutant compared to the NCTC8325 wild-type
Gene Product ΔairSR/WT ratioa
SAOUHSC_00114 cap5A Capsular polysaccharide biosynthesis protein, putative −3.61
SAOUHSC_00115 cap5B Capsular polysaccharide synthesis enzyme Cap5B −2.86
SAOUHSC_00116 cap8C Capsular polysaccharide synthesis enzyme Cap8C −2.91
SAOUHSC_00117 cap5D Capsular polysaccharide biosynthesis protein Cap5D −2.4
SAOUHSC_00119 cap8F Capsular polysaccharide synthesis enzyme Cap8F −2.34
SAOUHSC_00122 cap5I Capsular polysaccharide biosynthesis protein Cap5I −2.1
SAOUHSC_00124 cap5K Capsular polysaccharide biosynthesis protein Cap5K −2.18
SAOUHSC_00126 cap8M Capsular polysaccharide biosynthesis protein Cap8M −2.02
SAOUHSC_00127 cap5N Cap5N protein/UDP-glucose 4-epimerase, putative −2.14
SAOUHSC_00222 tagB TagB protein, putative 2.24
SAOUHSC_00295 nanA N-acetylneuraminate lyase −2.02
SAOUHSC_00469 spoVG Regulatory protein SpoVG −2.51
SAOUHSC_00545 sdrD sdrD protein, putative −3.68
SAOUHSC_00640 tagA Teichoic acid biosynthesis protein −2.08
SAOUHSC_00812 clfA Clumping factor, ClfA −4.72
SAOUHSC_00918 Truncated MHC class II analog protein 2.15
SAOUHSC_00953 Diacylglycerol glucosyltransferase −2.21
SAOUHSC_00974 Glycosyl transferase, group 1 4.24
SAOUHSC_01106 murI Glutamate racemase, MurI −2.12
SAOUHSC_01145 pbp1 Penicillin-binding protein 1 −2.05
SAOUHSC_01147 murD UDP-N-acetylmuramoylalanine--D-glutamate ligase, MurD −2.58
SAOUHSC_01148 ftsQ Cell division protein, putative −2.38
SAOUHSC_01346 Glycine betaine transporter, putative 4.62
SAOUHSC_01400 Alanine racemase, putative −2.81
SAOUHSC_02317 murF UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase −2.3
SAOUHSC_02318 ddl D-alanyl-alanine synthetase A −2.34
SAOUHSC_02399 glmS Glucosamine--fructose-6-phosphate aminotransferase −2.05
SAOUHSC_02444 Osmoprotectant transporter, BCCT family, opuD-like protein −2.86
SAOUHSC_02998 cap5C Capsular polysaccharide biosynthesis protein, Cap5C 2.04

a “-” indicates down-regulated in the airSR mutant.

Sun et al.

Sun et al. BMC Microbiology 2013 13:286   doi:10.1186/1471-2180-13-286

Open Data