Open Access Research article

Multilocus sequence analysis of Treponema denticola strains of diverse origin

Sisu Mo1, Meng You2, Yvonne CF Su3, Donnabella C Lacap-Bugler2, Yong-biao Huo1, Gavin JD Smith3, W Keung Leung2 and Rory M Watt1*

Author Affiliations

1 Oral Biosciences, Faculty of Dentistry, The University of Hong Kong, Prince Philip Dental Hospital, 34 Hospital Road, Sai Ying Pun, Hong Kong

2 Oral Diagnosis and Polyclinics, Faculty of Dentistry, The University of Hong Kong, Prince Philip Dental Hospital, 34 Hospital Road, Sai Ying Pun, Hong Kong

3 Program in Emerging Infectious Diseases, Duke-NUS Graduate Medical School Singapore, 8 College Road, Singapore, 169857, Singapore

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BMC Microbiology 2013, 13:24  doi:10.1186/1471-2180-13-24

Published: 4 February 2013

Additional files

Additional file 1:

Table summarizing G + C content (%) for the eight genes selected for sequence analysis within the 20 Treponema denticola strains.

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Additional file 2:

Table summarizing details of the flaA, recA, pyrH, ppnK, dnaN, era and radC gene homologues present in Treponema pallidum SS14 and Treponema vincentii LA-1 (ATCC 35580).

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Additional file 3:

Table summarizing the optimal models and parameter values for the individual gene and concatenated flaA − recA − pyrH − ppnK − dnaN − era − radC gene datasets analyzed in this study.

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Additional file 4:

Maximum likelihood (ML) phylogenetic trees obtained for the individual 16S rRNA, flaA, recA, pyrH, ppnK, dnaN, era and radC gene datasets.

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