Table 2

COG category of differentially-expressed genes in NCTC 11168 in response to treatment with a sub-inhibitory dose of Ery
COG category No. up-regulated (%)* No. down-regulated (%)* Total No. differentially expressed genes
Amino acid transport and metabolism 6 (4.76%) 5 (3.97%) 11
Carbohydrate transport and metabolism 1 (2.94%) 2 (5.88%) 3
Cell motility 2 (3.85%) 0 (0.00%) 2
Cell wall/membrane biogenesis 0 (0.00%) 3 (2.52%) 3
Coenzyme transport and metabolism 1 (1.45%) 2 (2.90%) 3
Defense mechanisms 1 (4.35%) 1 (4.35%) 2
Function unknown 4 (5.63%) 3 (4.23%) 7
General function prediction only 2 (1.41%) 2 (1.41%) 4
Inorganic ion transport and metabolism 3 (3.70%) 2 (4.94%) 5
Lipid transport and metabolism 1 (2.86%) 2 (5.71%) 3
Poorly characterized 15 (2.81%) 17 (5.71%) 32
Posttranslational modification, chaperones 0 (0.00%) 1 (1.54%) 1
Replication, recombination and repair 0 (0.00%) 1 (1.67%) 1
Signal transduction mechanisms 1 (2.22%) 2 (4.44%) 3
Transcription 2 (4.65%) 2 (4.65%) 4
Translation 0 (0.00%) 1 (1.00%) 1
Total 39 46 85

* This percentage was calculated based on the number of the up or down regulated genes in a category to the total number of the genes in that particular category.

Xia et al.

Xia et al. BMC Microbiology 2013 13:133   doi:10.1186/1471-2180-13-133

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