Table 2

Mutational events in the inlA gene
Sequence types (na) Number of strains and level of virulenceb Serotype Genotypic Group inlA Location of premature stop codonc Mutation
Nucleotide Event Typesd
31 (n = 8) 4 LV 1/2a Ib 564 C-to-T transition 189 5
4 V 1/2a 12 deletion 1 nt 9 4
13 (n = 11) 11 LV 1/2a Ia 228 C-to-T transition 77 15
193 (n = 8) 8 LV 1/2a IIIa 13 insertion 1 nt 26 -
196 (n = 1) 1 V 1/2a 13 insertion 1 nt 26 -
9 (n = 8) 2 LV; 2 V 1/2c; 3c; 1/2a IIIb 1636 deletion 1 nt 577 12
2 V 1/2c; 3c 2053 G-to-A transition 685 11
1 V 1/2a 1614 C-to-T transition 539 14
6 (n = 2) 1 V 4b 2219 deletion 9 nt - -
194 (n = 1) 1 V 4b 2219 deletion 9 nt - -

a Number of strains in the sequence types.

b Number of strains with the inlA event and level of virulence: V (virulent) or LV (low-virulence).

c Numbers represent the amino acid position of each respective premature stop codon in InlA. The deletion of 9 nucleotides for the 2 last ST did not generate any premature stop codon.

d Mutation types according to Van Stelten et al.[17].

Roche et al.

Roche et al. BMC Microbiology 2012 12:304   doi:10.1186/1471-2180-12-304

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