Mass spectral analysis of BoNT/E9. Panel A shows the products of endopeptidase cleavage of a type E specific peptide substrate detected by mass spectrometry. Peaks indicating the cleavage of the substrate by the toxin are marked with asterisks. Panel B illustrates the sequence coverage of BoNT/E9 amino acid sequence determination (in red font) of tryptic digestion products using mass spectrometry.
Raphael et al. BMC Microbiology 2012 12:245 doi:10.1186/1471-2180-12-245