Table 2

Molecular features of 28 high-level rifampicin-resistant S. aureus isolates
MLST (ST) SCCmec type spa-type Number of isolates Nucleotide mutation Amino acid substitution Resistance pattern
ST239 III t030 24
    C
AT/
    A
AT+T
    T
A/T
    C
A
481His/Asn+466Leu/Ser CIP+E+GEN+TET(1)
CIP+E+GEN+TET+CC(23)
1
    C
AT/
    A
AT+G
    C
T/G
    A
T
481His/Asn+477Ala/Asp CIP+E+GEN+TET+CC (1)
ST239 III t021 2
    C
AT/
    A
AT+T
    T
A/T
    C
A
481His/Asn+466Leu/Ser CIP+E+GEN+TET+CC(2)
ST239 III t045 1
    C
AT/
    A
AT+T
    T
A/T
    C
A
481His/Asn+466Leu/Ser CIP+E+GEN+TET+CC+SXT(1)

CIP, ciprofloxacin; E, erythromycin; CC, clindamycin; TET, tetracycline; SXT, sulfamethoxazole/trimethoprim; GEN, gentamycin; QD, quinupristin/dalfopristin.

Zhou et al.

Zhou et al. BMC Microbiology 2012 12:240   doi:10.1186/1471-2180-12-240

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