Table 1 |
||||||
| The characteristics of the rifampicin-resistant S. aureus isolates studied | ||||||
| MRSA rpoB mutations | Number of isolates | Mutation frequency % | Rifampicin MIC | Resistance pattern | ||
| Nucleotide mutation | Amino acid substitution | MIC(mg/L) | Number of isolates | |||
| TCA/TTA | 486Leu/Ser | 4 | 4.5% | 4 | 4 | CIP+E+GEN+TET(3) |
| CIP+E+GEN+TET+CC (1) | ||||||
| CAT/AAT | 481His/Asn | 1 | 1.1% | 4 | 1 | CIP+E+GEN+TET(1) |
| CAT/AAT+TTA/TCA | 481His/Asn+466Leu/Ser | 45 | 87.5% | 32 | 45 | CIP+E+GEN+TET(7) |
| CIP+E+GEN+TET+CC (35) | ||||||
| CIP+E+GEN+TET+CC+SXT(2) | ||||||
| CIP+E+GEN+TET+CC+SXT+QD(1) | ||||||
| CAT/AAT+TTA/TCA | 481His/Asn+466Leu/Ser | 14 | 64 | 14 | CIP+E+GEN+TET+CC (12) | |
| CIP+E+GEN+TET+CC +SXT(2) | ||||||
| CAT/AAT+TTA/TCA | 481His/Asn+466Leu/Ser | 11 | 128 | 11 | CIP+E+GEN+TET+CC (8) | |
| CIP+E+GEN+TET+CC +SXT(3) | ||||||
| CAT/AAT+TTA/TCA | 481His/Asn+466Leu/Ser | 7 | 256 | 7 | CIP+E+GEN+TET+CC +SXT(7) | |
| CAT/AAT+GCT/GAT | 481His/Asn+477Ala/Asp | 5 | 5.7% | 64 | 5 | CIP+E+GEN+TET+CC (5) |
| CAT/AAT+TTA/TCA+GCT/GAT | 481His/Asn+466Leu/Ser+477Ala/Asp | 1 | 1.1% | 128 | 1 | CIP+E+GEN+TET+CC (1) |
Zhou et al. BMC Microbiology 2012 12:240 doi:10.1186/1471-2180-12-240
