Table 1

The characteristics of the rifampicin-resistant S. aureus isolates studied
MRSA rpoB mutations Number of isolates Mutation frequency % Rifampicin MIC Resistance pattern
Nucleotide mutation Amino acid substitution MIC(mg/L) Number of isolates
T
    C
A/T
    T
A
486Leu/Ser 4 4.5% 4 4 CIP+E+GEN+TET(3)
CIP+E+GEN+TET+CC (1)
    C
AT/
    A
AT
481His/Asn 1 1.1% 4 1 CIP+E+GEN+TET(1)
    C
AT/
    A
AT+T
    T
A/T
    C
A
481His/Asn+466Leu/Ser 45 87.5% 32 45 CIP+E+GEN+TET(7)
CIP+E+GEN+TET+CC (35)
CIP+E+GEN+TET+CC+SXT(2)
CIP+E+GEN+TET+CC+SXT+QD(1)
    C
AT/
    A
AT+T
    T
A/T
    C
A
481His/Asn+466Leu/Ser 14 64 14 CIP+E+GEN+TET+CC (12)
CIP+E+GEN+TET+CC +SXT(2)
    C
AT/
    A
AT+T
    T
A/T
    C
A
481His/Asn+466Leu/Ser 11 128 11 CIP+E+GEN+TET+CC (8)
CIP+E+GEN+TET+CC +SXT(3)
    C
AT/
    A
AT+T
    T
A/T
    C
A
481His/Asn+466Leu/Ser 7 256 7 CIP+E+GEN+TET+CC +SXT(7)
    C
AT/
    A
AT+G
    C
T/G
    A
T
481His/Asn+477Ala/Asp 5 5.7% 64 5 CIP+E+GEN+TET+CC (5)
    C
AT/
    A
AT+T
    T
A/T
    C
A+G
    C
T/G
    A
T
481His/Asn+466Leu/Ser+477Ala/Asp 1 1.1% 128 1 CIP+E+GEN+TET+CC (1)

Zhou et al.

Zhou et al. BMC Microbiology 2012 12:240   doi:10.1186/1471-2180-12-240

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