Table 1

Distribution of phenotypes and genotypes among macrolide-resistant S. pyogenes isolates
Phenotype No. isolates (%) Invasive/non-invasive Antimicrobial agent(mg/L) Macrolide resistance genotype
Range MIC50 MIC90 erm(B) erm(A) mef(A) msr(D) None gene
M 227 (76.9) Erythromycin 1- ≥ 256 32 128 50 87 224 221 1
38 / 189 Clindamycin 0.06-0.5 0.25 0.5
cMLSB 60 (20.3) Erythromycin 8- ≥ 256 ≥256 ≥256 57 11 36 17 2
32 / 28 Clindamycin 1- ≥ 256 ≥256 ≥256
iMLSB 8 (2.7) Erythromycin 2- ≥ 256 16 32 3 8 4 3 0
3 / 5 Clindamycin 0.06-0.5 0.25 0.5
Total 295 (100) Erythromycin 1- ≥ 256 64 256 110 106 264 241 3
73 /222 Clindamycin 0.06-0.5 0.25 256

Rubio-López et al.

Rubio-López et al. BMC Microbiology 2012 12:215   doi:10.1186/1471-2180-12-215

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