Table 3

Antibiotic resistance gene profiles of the 21E. faeciumstrains
Gene cat ermA ermB aad6 aad9 aadE aacA- aphD tetL tetM vanA gyrAb parCc pbp5-Rd
Resistance CHL ERY ERY SPC/ STR SPC/ STR SPC/ STR GEN TET TET VAN CIP CIP AMP
Strains
1,141,733
Com12
Com15
E980
TX1330
1,230,933 X X X X X X X X X
1,231,408 X X X X X X X
1,231,410 X X X X X X
1,231,501
1,231,502 X X X X X X X X
C68 X X X X X X X X
D344SRFa X X X X X
TX16 X X X X X X X
E1039 X
E1071 X X X X X X X X
E1162 X X X
E1636 X X
E1679 X X X X X X X X X
TX82 X X X X X X X X
TX0133A X X X X X X X X X
U0317 X X X X X X X

aA rifampin- and fusidic acid-resistant derivative of clinical strain E. faecium D344S in which the spontaneous loss of pbp5 and its surrounding region resulted in an ampicillin-susceptible phenotype.

bAmino acid change (E to K/G) in residue 87 or (S to R/Y/I) in residue 83 of GyrA.

cAmino acid change (E to K) in residue 86 or (S to R/I) in residue 82 of ParC.

dConsensus sequence of the pbp5-R allele encoding the low affinity Pbp5-R.

eTC6 was not included in this analysis as it is a transconjugant of C68 and D344SRF, so therefore is not a unique genome.

Qin et al.

Qin et al. BMC Microbiology 2012 12:135   doi:10.1186/1471-2180-12-135

Open Data