Table 2

Gene Ontology (GO) term analysis for the C. neoformans FLC response

GO group

GO subgroup

P-value


Up-regulated genes

Oxidation reduction

5.26e-10

Small molecule metabolic process

1.34e-06

Alcohol metabolic process

4.74e-07

Sterol metabolic process

4.41e-07

Steroid metabolic process

7.81e-07

Phytosteroid metabolic process

1.47e-09

Steroid biosynthetic process

9.08e-07

Ergosterol biosynthetic process

3.57e-08

Transmembrane transport

0.00076


Down-regulated genes

Oxidation reduction

1.31e-12

Small molecule metabolic process

2.50e-11

Alcohol metabolic process

0.00037

Cellular ketone metabolic process

1.25e-08

Cellular amino acid and derivative metabolic process

3.74e-12

Organic acid metabolic process

1.63e-08

Amine metabolic process

1.47e-13

Gamma-aminobutyric acid metabolic process

0.00078


GO term assignment for C. neoformans H99 genes was based on homology to S. cerevisiae genes. P-value represents the probability that a particular GO term is enriched in the microarray gene list. The P-value cut-off was < 0.05.

Florio et al. BMC Microbiology 2011 11:97   doi:10.1186/1471-2180-11-97

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