Table 4

Comparative analysis of the allelic variation in bla locus for MRSA and MSSA strains

No. isolates

No. alleles

Simpson's

Unique SNP

SNP/allele (average)

Mutations per allele (average)

dN/dS



ID

CI (95%)

Silent

Conserv.

Missense

Nonsense

Average

St. dev.


blaZ

54

11

79.2

69.6-88.8

41

11.4

5.3

1.7

3.7

0.1

0.21

0.11

MRSA

blaI

27

7

82.1

74.6-89.5

10

3.9

2.9

0

1.0

0

0.11

0.05

blaR1

31

10

88.8

83.2-94.4

60

24.4

9.7

5.3

8.0

0

0.24

0.11


blaZ

24

9

76.1

61.3-90.9

35

14.7

7.1

1.9

4.6

0

0.17

0.04

MSSA

blaI

20

6

74.2

60.5-87.9

9

2.5

1.5

0.2

0.8

0

0.08

0.03

blaR1

17

8

88.2

81.2-95.3

61

24.6

10.4

5.5

7.8

0

0.24

0.10


blaZ

78

13

81.1

75.0-87.3

43

12.4

5.8

1.8

4.0

0.1

0.20

0.10

All

blaI

47

9

78.4

71.0-85.9

13

3.4

2.3

0.1

1.0

0

0.10

0.04

blaR1

48

12

88.5

84.0-93.0

65

24.8

10.2

5.3

8.1

0

0.25

0.10


ID, index of diversity; CI, confidence interval; SNP, single-nucleotide polymorphism; Conserv., conservative; St. dev., standard deviation

Milheiriço et al. BMC Microbiology 2011 11:76   doi:10.1186/1471-2180-11-76

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