Table 4 |
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|
Comparative analysis of the allelic variation in bla locus for MRSA and MSSA strains |
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|
No. isolates |
No. alleles |
Simpson's |
Unique SNP |
SNP/allele (average) |
Mutations per allele (average) |
dN/dS |
|||||||
|
|
|
||||||||||||
|
ID |
CI (95%) |
Silent |
Conserv. |
Missense |
Nonsense |
Average |
St. dev. |
||||||
|
|
|||||||||||||
|
blaZ |
54 |
11 |
79.2 |
69.6-88.8 |
41 |
11.4 |
5.3 |
1.7 |
3.7 |
0.1 |
0.21 |
0.11 |
|
|
MRSA |
blaI |
27 |
7 |
82.1 |
74.6-89.5 |
10 |
3.9 |
2.9 |
0 |
1.0 |
0 |
0.11 |
0.05 |
|
blaR1 |
31 |
10 |
88.8 |
83.2-94.4 |
60 |
24.4 |
9.7 |
5.3 |
8.0 |
0 |
0.24 |
0.11 |
|
|
|
|||||||||||||
|
blaZ |
24 |
9 |
76.1 |
61.3-90.9 |
35 |
14.7 |
7.1 |
1.9 |
4.6 |
0 |
0.17 |
0.04 |
|
|
MSSA |
blaI |
20 |
6 |
74.2 |
60.5-87.9 |
9 |
2.5 |
1.5 |
0.2 |
0.8 |
0 |
0.08 |
0.03 |
|
blaR1 |
17 |
8 |
88.2 |
81.2-95.3 |
61 |
24.6 |
10.4 |
5.5 |
7.8 |
0 |
0.24 |
0.10 |
|
|
|
|||||||||||||
|
blaZ |
78 |
13 |
81.1 |
75.0-87.3 |
43 |
12.4 |
5.8 |
1.8 |
4.0 |
0.1 |
0.20 |
0.10 |
|
|
All |
blaI |
47 |
9 |
78.4 |
71.0-85.9 |
13 |
3.4 |
2.3 |
0.1 |
1.0 |
0 |
0.10 |
0.04 |
|
blaR1 |
48 |
12 |
88.5 |
84.0-93.0 |
65 |
24.8 |
10.2 |
5.3 |
8.1 |
0 |
0.25 |
0.10 |
|
|
|
|||||||||||||
|
ID, index of diversity; CI, confidence interval; SNP, single-nucleotide polymorphism; Conserv., conservative; St. dev., standard deviation |
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|
Milheiriço et al. BMC Microbiology 2011 11:76 doi:10.1186/1471-2180-11-76 |
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