Table 1

Candida isolates used in this study and their susceptibility to antifungals and interactions with G. mellonella

Microorganisms

Susceptibility to Antifungal (MIC)

Galleria mellonella


Specie of

Candida

Strain of

Candida

Clinical

isolate

Fluconazole

(μg/mL)

Amph B

(μg/mL)

CFU/larva

injected

Number of killing/total

Medium time to mortality (h)


C. albicans

4S

Saliva

0.125

0.25

7.1 × 105

16/16

18

10S

Saliva

0.125

0.5

5.2 × 105

16/16

18

24S

Saliva

0.125

0.5

9.4 × 105

16/16

18

31S

Saliva

0.125

0.5

5.0 × 105

16/16

24

39S

Saliva

Resistant

0.25

5.9 × 105

16/16

18

48S

Saliva

0.125

0.25

6.7 × 105

16/16

18

60S

Saliva

0.125

0.25

6.3 × 105

16/16

18

3

OPC

0.5

0.25

7.2 × 105

16/16

18

14

OPC

Resistant

0.25

5.7 × 105

16/16

18

21

OPC

Resistant

0.25

7.5 × 105

16/16

18

37

OPC

Resistant

0.25

5.5 × 105

16/16

18

CAL006

Blood culture

0.125

0.5

1.9 × 105

16/16

24

CAL007

Peritoneal fluid

2

0.25

4.5 × 105

16/16

24

CAL008

Peritoneal fluid

1

0.5

7.2 × 105

16/16

18

CAL009

Blood culture

1

0.5

4.7 × 105

16/16

18

CAL010

Subdiaphragnatic

1

0.5

4.8 × 105

16/16

18

C. tropicalis

12

OPC

0.5

0.25

3.9 × 105

16/16

18

140S

Saliva

0.125

0.25

4.9 × 105

16/16

18

CTR002

Synovial fluid

Resistant

0.5

9.1 × 105

16/16

18

CTR003

Abdominal fluid

2

0.5

5.0 × 105

16/16

18

C. parapsilosis

127S

Saliva

1

0.5

6.2 × 105

16/16

18

CPA001

Lung tissue

4

0.5

7.3 × 105

16/16

21

C. glabrata

12S

Saliva

2

0.5

6.4 × 105

2/16

-

45

OPC

4

0.5

9.8 × 105

6/16

-

55

OPC

4

0.5

1.0 × 106

0/16

-

CGL002

Drainage

32

0.5

4.0 × 105

0/16

-

CGL003

Jackson-Pratt fluid

32

0.5

5.4 × 105

8/16

-

C. dubliniensis

18S

Saliva

16

0.25

3.9 × 105

16/16

18

155S

Saliva

0.5

0.25

5.1 × 105

16/16

18

C. lusitaniae

CLU005

Blood culture

2

1

1.4 × 105

14/16

-

C.norvegensis

52S

Saliva

32

0.5

6.3 × 105

6/16

-

C. krusei

58

OPC

Resistant

2

8.8 × 105

4/16

-

C. kefyr

CKE002

Blood culture

2

1

4.2 × 105

2/16

-


Junqueira et al. BMC Microbiology 2011 11:247   doi:10.1186/1471-2180-11-247

Open Data