Table 2

Virulence of Streptococcus suis serotype 1 and 9 strains determined in pigs.

S. suis

strain

Sero-type

Dose

No. of pigs

Mortality

(%)

Mean time until death (days)

Specific

Clinical

Signs1

Non-

Specific

Clinical

Signs2

Path.

CNS

Bact.

CNS

Path.

serosae

Bact.

serosae

Path.

joints

Bact.

joints


6388

1

106 CFU$

5CD

100

2

17

37

4

4

4

4

2

4

6112

1

106 CFU$

4CD

100

2

7

36

3

4

1

4

0

4

NCTC10273R1

1

106 CFU$

4CD

100

9.8

6

21

1

2

1

2

4

4

3

2

106 CFU$

4CD

50

7

4

67

0

0

4

3

0

0


3

2

106 CFU$

4CD

50

7.5

25

87

3

3

3

1

2

3

5973

9

106 CFU$

5CD

0

NA

0

0

0

0

2

1

0

0

22083R9

9

106 CFU$

4CD

0

NA

0

0

0

0

0

0

0

1


22083R9

9

109 CFU

4SPF

0

NA

13

0

1

0

0

0

0

1

7997

9

109 CFU

4SPF

25

4

1

2

1

1

0

1

1

2

8067

9

109 CFU

4SPF

0

NA

10

1

0

0

1

0

1

0

28017

9

109 CFU

4SPF

25

1

1

0

1

1

2

0

1

2


$ Animals were predisposed with a B. bronchiseptica infection 2 days before infection with S. suis; CD caesarean-derived germfree piglets; SPF specific pathogen free piglets; 1 mean number of observations of nervous signs and lameness in one or more joints/total number of observations × 100%; 2 mean number of observations of inappetence and depression/total number of observations × 100%; Path. Pathology: number of pigs with pathological abnormalities; Bact. Bacteriology: Number of piglets from which S. suis is reisolated; NA, animals survived until the end of the experiment; CNS Central nervous system.

de Greeff et al. BMC Microbiology 2011 11:161   doi:10.1186/1471-2180-11-161

Open Data