Table 2

Comparison of amino acid sequence at G-H loop of VP1 of the viruses derived from different origins and full-length plasmids

Virus/plasmid

Encoded G-H loop amino acid sequencec

Additional amino acid changes in VP1


Asia1/JS/CHA/05

TTYGEESSRRGDLAALARRVNNRLPTS

-


Asia1/JSp1

TTYGEESSRRGDLAALARRVNNRLPTS

-

Asia1/JSp1c4

TTYGEESSRRDDLAALARRVSNRLPTS

N154S

Asia1/JSp1c8

TTYGEESSRRDDLAALARRVSNRLPTS

N154S

Asia1/JSp1c20

TTYGEESSRRDDLAALARRVSNRLPTS

N154S

Asia1/JSM4

TTYGEESSRRGDLAALARRVNNRLPTS

-

TTYGEESSRRSDLAALARRVNNRLPTS

-

Asia1/JSM6c20

TTYGEESSRRGDLAALARRVNNRLPTS

-

TTYGEESSRRSDLAALARRVNNRLPTS

-

pRDD

TTYGEESSRRDDLAALARRVSNRLPTS

-

pRSD

TTYGEESSRRSDLAALARRVSNRLPTS

-

pRGD

TTYGEESSRRGDLAALARRVSNRLPTS

-

FMDV-RDDa

TTYGEESSRRDDFAALARRVSNRLPTS

L146F

FMDV-RSDa

TTYGEESSRRSDLAALARRVSNRLPTS

N154S

FMDV-RGDa

TTYGEESSRRGDFAALARRVSNRLPTS

L146F

FMDV-RDD/pigb

TTYGEESSRRDDLAALARRVSNRLPTS

-

FMFV-RDD/bovineb

TTYGEESSRRDDLAALARRVSNRLPTS

-

FMDV-RSD/pigb

TTYGEESSRRSDLAALARRVSNRLPTS

-

FMDV-RSD/bovineb

TTYGEESSRRSDLAALARRVSNRLPTS

-


a The rescued viruses were passaged 20 times in cell culture.

b Virus recovered from vesicular lesions, away from the inoculation site.

c Sequence data were obtained by RT-PCR of the VP1 capsid region. The dashes represent receptor binding triplet of the viruses derived from different origins and full-length plasmids.

Li et al. BMC Microbiology 2011 11:154   doi:10.1186/1471-2180-11-154

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