Killing kinetics of chimera 2 against S. marcescens (A+C) and S. aureus (B+D) displayed as mean number of viable cells with standard error of the mean (SEM). The assays were performed in two independent experiments. Time-kill of the chimera was determined at MIC in MHB (grey solid) and PBS (grey punctuated) and compared to MilliQ-treated control in MHB (black solid) and PBS (black punctuated) for S. marcescens (A) and S. aureus (B). The effect of chimera concentration on time-kill was determined in MHB at ¼ MIC (dark grey), 1/2 MIC (light grey) and MIC (black punctuated) and compared with MilliQ-treated control (black solid) for S. marcescens and (C) and S. aureus (D).
Hein-Kristensen et al. BMC Microbiology 2011 11:144 doi:10.1186/1471-2180-11-144