Functional clustering of BCM induced genes. Functional terms significantly associated (p < 0.05, Benjamini correction for multiple testing) with BCM induced genes relative to PCM induced genes. Functional annotation clusters with an enrichment score greater than 1.5 were considered significant. (A) Analysis of significantly upregulated genes (fold change ≥1.5) revealed functional annotation clusters associated with response to bacteria and external stimuli, apoptosis, immune response and inflammation, and signal transduction. (B) Analysis of significantly downregulated genes (fold change ≤1.5) revealed functional annotation clusters associated with chromatin modification, transcription, and metabolism.
Secor et al. BMC Microbiology 2011 11:143 doi:10.1186/1471-2180-11-143