Table 1

Frequency and associations between virulence genes and E. coli pathogroups

Genetic element

Virulence gene

EHEC (n = 64)

n, % (95%-CI)a

typical EPEC (n = 73)

n, % (95%-CI)a

atypical EPEC (n = 235)

n, % (95%-CI)a

STEC (n = 52)

n, % (95%-CI)a

E. coli (n = 21)

n, % (95%-CI)a


pMAR2 [12]

bfpA

0, 0 (0;5.6)

68b , 93.2 c (84.7;97.7)

0, 0 (0;1.6)

0, 0 (0;6.8)

0, 0 (0;16.1)

pO157 [46]

ehxA

61, 95.3c (86.9;99.0)

0, 0 (0;4.9)

65, 27.7 (22.0;33.9)

26, 50.0 c (35.8;64.2)

0, 0 (0;16.1

pO157 [46]

espP

37, 57.8c (44.8;70.1)

1, 1.4 (0.03;7.4)

26, 11.1 (7.4;15.8)

14, 26.9c (15.6;41.0)

0, 0 (0;16.1)

pO157 [46]

etpD

19, 29.7c (18.9;42.4)

3, 4.1 (0.86;11.5)

79, 33.6c (27.6;40.0)

0, 0 (0;6.8)

0, 0 (0;16.1)

pO157 [46]

katP

36, 56.3c (43.3;68.6)

1, 1.4 (0.03;7.4)

40, 17 (12.4;22.4)

1, 1.9 (0.05;10.3)

0, 0 (0;16.1)

OI-71 [31]

nleA

47, 73.4c (60.9;83.7)

17, 23.3 (14.2;34.6)

119, 50.6c (44.1;57.2)

0, 0 (0;6.8)

0, 0 (0;16.1)

OI-71 [31]

nleF

45, 70.3c (57.6;81.1)

19, 26 (16.5;37.6

87, 37 (30.8;43.5)

0, 0 (0;6.8

0, 0 (0;16.1)

OI-71 [31]

nleH1-2

63, 98.4c (91.6;100.0)

60, 82.2 (71.5;90.2)

205, 87.2c (82.3;91.2)

0, 0 (0;6.8)

0, 0 (0;16.1)

OI-122 [31]

ent/espL2

64, 100.0c (94.4;100.0)

46, 63c (50.9;74.0)

129, 54.9 (48.3;61.4)

0, 0 (0;6.8)

0, 0 (0;16.1)

OI-122 [31]

nleB

64, 100.0c (94.4;100.0)

46, 63c (50.9;74.0)

129, 54.9 (48.3;61.4)

0, 0 (0;6.8)

0, 0 (0;16.1

OI-122 [31]

nleE

59, 92.2c (82.7;97.4)

46, 63c (50.9;74.0)

128, 54.5 (47.9;61.0)

0, 0 (0;6.8)

0, 0 (0;16.1)

OI-57 [31]

nleG5

33, 51.6c (38.7;64.2)

9, 12.3 (5.8;22.1)

38, 16.2 (11.7;21.5)

0, 0 (0;6.8)

0, 0 (0;16.1)

OI-57 [31]

nleG6-2

57, 89.1c (78.7;95.5)

9, 12.3 (5.8;22.1)

107, 45.5c (39.0;52.1)

0, 0 (0;6.8)

0, 0 (0;16.1)

CP-933N [31]

espK

59, 92.2c (82.7;97.4)

14, 19.2 (10.9;30.1)

68, 28.9 (23.2;35.2)

0, 0 (0;6.8)

0, 0 (0;16.1)

Stx-phage [47]

stx1

39, 60.9c (47.9;72.9)

0, 0 (0;4.9)

0, 0 (0;1.6)

18, 34.6c (22.0;49.1)

0, 0 (0;16.1)

Stx-phage [31]

stx2

33, 51.6c (38.7;64.2)

0, 0 (0;4.9)

0, 0 (0;1.6)

48, 92.3c (81.5;97.9)

0, 0 (0;16.1)

LEE [31]

eae

64, 100.0c (94.4;100.0)

73, 100c (95.1;100.0)

235, 100c (98.4;100.0)

0, 0 (0;6.8)

0, 0 (0;16.1)


a) absolute (n) and relative frequencies (%) are shown and the exact 95% confidence level (95%-CI) [48]; b) five strains have lost the EAF plasmid encoding bfpA upon subculture; c) standardized residuals > 1 indicates a major influence on a significant chi-square test.

Bugarel et al. BMC Microbiology 2011 11:142   doi:10.1186/1471-2180-11-142

Open Data