The change in cell size homeostasis in response to YgjD depletion depends on (p)ppGpp. A) Changes in cell elongation rate and the interval between two divisions during YgjD depletion, for TB80 (ppGpp+) and TB84 (ppGpp0). For each strain, means and standard errors of three independent experiments are shown. In TB80, cell elongation rate starts to decrease after generation 3, and cells divide before they double in size. In TB84, cell division occurs close to the moment of cell size doubling (the means are close to the contour line of constant cell size). B) Change of mean cell size during YgjD depletion, for and TB80 (ppGpp+) and TB84 (ppGpp-). In TB80, cell size starts to decrease after generation 3, as a consequence of cell division that occurs before cells double in size (see panel A). In TB84, cell size decreases only slightly, and then increases after generation 5, when cells divide after the moment of cell doubling (see panel A).
Bergmiller et al. BMC Microbiology 2011 11:118 doi:10.1186/1471-2180-11-118