Quantitative analysis of myotube formation percentage during myogenesis in T. gondii infected cultures. (A) In uninfected cultures, after 3 days, the percentage of myotubes was 19.5% while in infected cultures, after 24 h of interaction, this percentage decreased to 2.5%. Note the 75% reduction in the formation of myotubes in infected cultures. Student's T-test (*) p = 0.0025. (B) Differential interference contrast (DIC) image showing influence of the infection by T. gondii (24 h of interaction) on SkMC myogenesis. Parasite (thick arrows) and unfused myocytes (thin arrows).
Gomes et al. BMC Microbiology 2011 11:110 doi:10.1186/1471-2180-11-110