Table 1

Faecal microbiota composition of untreated and treated CD patients and age-matched healthy controls assessed by FISH and FCM

Microbial groups

Specific group-probed cells/EUB-388 cells (%)1


Untreated CD (n = 24)

Treated CD (n = 18)

Control (n = 20)


Median

Range

Median

Range

Median

Range


Bifidobacterium

7.73

22.08-3.27

9.20

33.82-1.58

12.54

33.68-6.94

C. histolyticum

5.26

27.61-0.71

9.41

39.60-2.95

11.61

35.69-0.16

C. lituseburense

3.23

27.24-0.17

4.41

29.85-0.28

6.83

19.56-1.05

Lactobacillus-Enterococcus

1.94

10.93-0.14

1.12

9.30-0.22

1.76

16.47-0.25

Staphylococcus

10.36

37.38-0.89

16.49

42.91-0.51

18.04

41.32-0.19

Bacteroides-Prevotella

3.54

20.85-0.80

2.61

15.07-0.25

2.32

5.53-0.33

E. coli

5.20

23.42-0.48

6.39

28.77-0.55

7.32

28.26-1.10

F. prausnitzii

6.03

37.50-1.07

11.09

37.84-2.95

13.88

37.08-2.32

Sulphate-reducing bacteria

9.58

38.02-2.84

9.82

41.74-2.09

10.02

36.92-2.92


1 Data were expressed as proportions of bacterial cells hybridising with group-specific probes to total bacteria hybridising with EUB probe 338.

* Statistical significant differences were calculated using the Mann-Whitney U-test and established at P < 0.050.

De Palma et al. BMC Microbiology 2010 10:63   doi:10.1186/1471-2180-10-63

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