Additional file 2.

Figure S1: Sequence alignments of the LRR domain in seventeen IRREKO@ LRR proteins. (A) Escherichia coli yddk; (B) Bifidobacterium animalis BIFLAC_05879; (C) Vibrio harveyi HY01 A1Q_3393; (D) Shewanella woodyi ATCC 51908 SwooDRAFT_0647; (E) Unidentified eubacterium SCB49 SCB49_09905; (F) Colwellia psychrerythraea CPS_3882; (G) Listeria monocytogenes lmo0331 protein; (H) Treponema denticola TDE_0593; (I) Polaromonas naphthalenivorans Pnap_3264; (J) Ddelta proteobacterium MLMS-1 MldDRAFT_4836; (K) Kordia algicida OT-1 KAOT1_04155; (L) Coprococcus eutactus ATCC 27759 COPEUT_03021; (M) Clostridiales bacterium 1_7_47_FAA Cbac1_010100006401; (N) Listeria lin1204/LMOf6854_0364; (O) Escherichia coli SMS-3-5 EcSMS35_1703; (P) Escherichia coli O157:H7 ECS2075/Z2240; (Q) Trichomonas vaginalis G3 TVAG_084780. Overall consensus sequences of IRREKO@LRRs - LxxLxLxxNxLxxLDLxx(N/L/Q/x)xx or LxxLxLxxNxLxxLDLxx(N/L/Q/x)xx - are shown. The consensus amino acids are highlighted with reverse-contrast. Also the consensus amino acids of "SDS22-like" LRR with the consensus of LxxLxLxxNxLxxLxxLxxLxx and of "Bacterial" LRR with the consensus of LxxLxxNxLxxLPxLPxx are highlighted with reverse-contrast. Cysteines of the cysteine clusters at the N-terminal side of LRR domain are shown by underlined bold letter. Cons., the overall consensus sequences of IRREKO@LRRs; SIGNAL, signal peptide sequence; LRR; leucine rich repeat (LRR); IRREKO, IRREKO LRR; SDS22; "SDS22-like" LRR; BAC; "Bacterial" LRR; ISLAND, Island region interrupting LRRs; N-TERM, the N-terminal region of proteins; C-TERM, the C-terminal region of proteins; LRRNT; the region of cysteine clusters at the N-terminal side of LRR domain.

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Matsushima et al. BMC Microbiology 2010 10:235   doi:10.1186/1471-2180-10-235