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Open Access Highly Accessed Database

BACTIBASE second release: a database and tool platform for bacteriocin characterization

Riadh Hammami12, Abdelmajid Zouhir2, Christophe Le Lay1, Jeannette Ben Hamida2 and Ismail Fliss1*

Author Affiliations

1 STELA Dairy Research Center, Nutraceuticals and Functional Foods Institute, Université Laval, G1K 7P4 Québec, QC, Canada

2 Unité de Protéomie Fonctionnelle & Biopréservation Alimentaire, Institut Supérieur des Sciences Biologiques Appliquées de Tunis, Université El Manar, Tunisie

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BMC Microbiology 2010, 10:22  doi:10.1186/1471-2180-10-22

Published: 27 January 2010

Abstract

Background

BACTIBASE is an integrated open-access database designed for the characterization of bacterial antimicrobial peptides, commonly known as bacteriocins.

Description

For its second release, BACTIBASE has been expanded and equipped with additional functions aimed at both casual and power users. The number of entries has been increased by 44% and includes data collected from published literature as well as high-throughput datasets. The database provides a manually curated annotation of bacteriocin sequences. Improvements brought to BACTIBASE include incorporation of various tools for bacteriocin analysis, such as homology search, multiple sequence alignments, Hidden Markov Models, molecular modelling and retrieval through our taxonomy Browser.

Conclusion

The provided features should make BACTIBASE a useful tool in food preservation or food safety applications and could have implications for the development of new drugs for medical use. BACTIBASE is available at http://bactibase.pfba-lab-tun.org webcite.