Table 1

The mean CFU counts (± SD) of Candida spp. and P. aeruginosa from both monospecies and dual species biofilms at 90 min, 24 h and 48 h.

Time

interval

Candida CFU (106) ± SD

P value

P. aeruginosa CFU (106) ± SD

P value



Control (MSB)

Test (DSB)

Control (MSB)

Test (DSB)


Candida

albicans

90 min

12.60 ± 2.19

5.29 ± 1.52

0.005

3.44 ± 2.20

0.66 ± 0.69

0.002

24 h

15.22 ± 3.31

5.00 ± 2.60

< 0.001

876.89 ± 206.39

719.56 ± 266.53

0.200

48 h

31.89 ± 6.60

0.22 ± 0.44

< 0.001

1358.89 ± 323.59

922.22 ± 186.60

0.009


Candida krusei

90 min

2.43 ± 1.46

2.71 ± 0.66

0.352

7.32 ± 3.82

2.78 ± 1.29

0.003

24 h

3.39 ± 2.00

2.49 ± 0.73

0.301

987.78 ± 341.79

583.33 ± 218.92

0.022

48 h

0.09 ± 0.14

0.22 ± 0.44

0.867

140.00 ± 48.73

73.33 ± 35.71

0.010


Candida tropicalis

90 min

9.81 ± 3.05

3.87 ± 2.29

0.004

1.42 ± 1.25

2.26 ± 0.71

0.070

24 h

27.67 ± 5.92

3.44 ± 1.59

< 0.001

431.11 ± 66.23

471.11 ± 162.90

0.534

48 h

4.22 ± 2.05

0.00 ± 0.00

< 0.001

98.89 ± 75.74

351.11 ± 162.51

0.002


Candida parapsilosis

90 min

10.60 ± 6.71

1.26 ± 1.34

< 0.001

4.87 ± 1.66

3.83 ± 2.31

0.228

24 h

2.11 ± 2.32

0.78 ± 0.44

0.364

412.22 ± 208.55

277.78 ± 162.69

0.121

48 h

0.89 ± 0.60

0.44 ± 0.73

0.120

183.33 ± 69.64

179.56 ± 50.02

0.859


Candida glabrata

90 min

10.81 ± 2.90

10.12 ± 3.97

0.659

9.91 ± 9.01

8.17 ± 5.03

0.691

24 h

35.78 ± 21.72

15.00 ± 21.08

0.024

328.89 ± 88.94

56.67 ± 15.81

< 0.001

48 h

28.22 ± 17.14

0.11 ± 0.33

< 0.001

128.89 ± 69.54

28.89 ± 17.64

< 0.001


Candida dubliniensis

90 min

9.34 ± 3.21

2.94 ± 1.50

< 0.001

9.83 ± 2.33

6.51 ± 4.35

0.070

24 h

5.81 ± 2.46

0.54 ± 0.88

< 0.001

878.89 ± 286.07

461.11 ± 142.78

0.003

48 h

0.00 ± 0.00

0.00 ± 0.00

1.000

97.78 ± 48.16

52.22 ± 50.94

0.056


P < 0.05 was considered statistically significant. Significant differences are shown in bold text.

Bandara et al. BMC Microbiology 2010 10:125   doi:10.1186/1471-2180-10-125

Open Data