Table 1 |
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Comparison of suitability of QATED, PCR-RFLP and serotyping for employment of outbreak analysis in the routine diagnostic laboratory |
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Laboratory parameter |
QATED† |
PCR- |
Serotyping |
|
RFLP* |
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|
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Time to result |
24 h |
9 h |
2 h |
|
Relative cost/isolate |
moderate |
high |
high |
|
Ease of use |
simple |
complex |
average |
|
Repeatability |
good |
good |
good |
|
Requirements for complex equipment |
average |
high |
average |
|
Applicability to routine diagnostic |
good |
poor |
poor1 |
|
laboratory |
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†QATED, quantitative antibiogram typing based on Euclidean distance, * RFLP, restriction fragment length polymorphism; 1. Based on difficulty in obtaining quality antisera |
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Moore and Goldsmith BMC Microbiology 2001 1:13 doi:10.1186/1471-2180-1-13 |
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