Small-bowel mucosal transglutaminase 2 (TG2, red)-specific IgA deposits (green) after 24 hours' organ culture. A) Positive staining (arrow) in the mucosal villous of a short-term treated celiac disease patient (gluten-free diet for three years). B) Negative IgA deposits (arrow) in the small-bowel mucosa of long-term treated celiac disease patient (gluten-free diet for eight years). Co-localization of IgA deposits with TG2 is shown in yellow. Magnification 40×.
Stenman et al. BMC Immunology 2008 9:6 doi:10.1186/1471-2172-9-6