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Up-regulation of immune response genes in skeletal muscles of patients with active JDM longer than 2 months (Cluster C and D; genes are in order shown in figure 1) |
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| Affymetrix accession |
p-value |
Fold change (long/short) |
Gene description |
|
|
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| Cluster C |
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| 203981_s_at |
6.2E-03 |
1.5 |
ATP-binding cassette, sub-family D (ALD), member 4 |
| 210105_s_at |
1.5E-03 |
1.6 |
FYN oncogene related to SRC, FGR, YES |
| 214430_at |
1.4E-03 |
1.6 |
galactosidase, alpha |
| 200602_at |
6.5E-04 |
2.0 |
amyloid beta (A4) precursor protein |
| 201103_x_at |
5.7E-03 |
1.4 |
hypothetical protein LOC200030 |
| 209765_at |
2.3E-03 |
1.6 |
a disintegrin and metalloproteinase domain 19 |
| 216510_x_at |
9.6E-04 |
5.6 |
immunoglobulin heavy constant gamma 1 |
| 201069_at |
3.9E-03 |
2.0 |
matrix metalloproteinase 2 |
| 203473_at |
1.1E-04 |
2.2 |
solute carrier organic anion transporter family, member 2B1 |
| 203742_s_at |
1.9E-03 |
1.5 |
thymine-DNA glycosylase |
| 205917_at |
6.5E-04 |
1.6 |
ZNF264 |
| 212671_s_at |
2.5E-04 |
5.6 |
major histocompatibility complex, class II, DQ alpha 1/2 |
| Cluster D |
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| 218376_s_at |
4.1E-03 |
2.5 |
NEDD9 interacting protein with calponin homology and LIM domains |
| 209079_x_at |
9.1E-04 |
1.6 |
protocadherin gamma subfamily |
| 38671_at |
5.9E-04 |
1.6 |
plexin D1 |
| 201279_s_at |
2.0E-03 |
1.6 |
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) |
| 211066_x_at |
6.5E-04 |
1.6 |
protocadherin gamma subfamily |
| 215599_at |
3.8E-04 |
2.1 |
SMA4 |
| 205717_x_at |
1.8E-03 |
1.4 |
protocadherin gamma subfamily |
| 217659_at |
1.3E-03 |
1.6 |
KIAA0261 |
| 212607_at |
1.1E-04 |
1.3 |
AKT3 (protein kinase B, gamma) |
| 211748_x_at |
4.0E-03 |
2.4 |
prostaglandin D2 synthase 21 kDa (brain) |
| 215376_at |
2.4E-04 |
1.4 |
CDNA FLJ12295 fis, clone MAMMA1001818 |
| 202259_s_at |
1.1E-04 |
1.6 |
phosphonoformate immuno-associated protein 5 |
| 212187_x_at |
2.1E-03 |
1.9 |
prostaglandin D2 synthase 21 kDa (brain) |
| 206666_at |
3.7E-04 |
2.5 |
granzyme K (serine protease, granzyme 3; tryptase II) |
| 217947_at |
5.9E-04 |
1.9 |
chemokine-like factor super family 6 |
Chen et al. BMC Immunology 2008 9:43 doi:10.1186/1471-2172-9-43 |
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