Table 1

Physiochemical functionality of peptide side chains.

Pocket specificity

Associated amino acid residues


Acidic

DE

Aliphatic

LIVMQ

Aromatic

FWY

Aromatic and aliphatic

FWYLIVMQ

Aromatic and basic

YRK

Aromatic and large hydrophobic

FWYLIM

Basic

RHK

Hydrophobic

LIVMFWYA

Large hydrophobic

FLIM

Proline

P

Small

AST

Small and aliphatic

ATSVLIMQ

Small hydrophobic

AV

Small, aliphatic and aromatic

ASTVLIMQFWY


Sidney et al. BMC Immunology 2008 9:1   doi:10.1186/1471-2172-9-1

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