Table 3 |
|
|
Discriminators of BCG effects versus TNF and LPS over time. |
|
|
Analyte |
p value |
|
|
|
|
GM-CSF |
0.001 |
|
IL-1 beta |
0.007 |
|
IL-2 |
0.006 |
|
IL-3 |
0.032 |
|
IL-4 |
0.016 |
|
IL-6 |
0.000 |
|
IL-10 |
0.001 |
|
IL-12p70 |
0.012 |
|
IL-17 |
0.002 |
|
KC |
0.018 |
|
RANTES* |
0.001 |
|
|
|
|
Urinary cytokines response over time was determined using a mixed modeling approach, according to the following equation: Cytokine Level = (a) * Time + (b) Trx * Time, where Trx is BCG vs LPS & TNF-Alpha. A variance component covariance matrix was used to account for the correlation structure inherent in longitudinal measurements of cytokines.*Time squared interaction. |
|
|
Saban et al. BMC Immunology 2007 8:6 doi:10.1186/1471-2172-8-6 |
|
