Table 1

T cell sub-populations in mAb treated mice. FACS analysis of splenocytes collected from untreated and antibody-treated CBA mice (1 mg YTS177 and 1 mg YTS105 ip given on days -28, -26 and -24 relative to data collection on day 0). 'Total splenocytes' refers to all cells in the lymphocyte forward- and side-scatter gate. NS (not significant) p > 0.05; (**) p < 0.001.

Cell phenotype

Untreated, n = 6(mean +/- SD)%

AntiCD4 + antiCD8 treated, n 6 (mean +/- SD)%

p value


(CD3+CD8+/total splenocytes)

20.8 +/- 2.6

1.8 +/- 0.6

**

# (CD44+ /CD8+)

6.9 +/- 0.8

36.7 +/- 6.4

**

(CD3+CD4+ /total splenocytes)

32.0 +/- 6.2

37.8 +/- 6.2

NS

# (CD25+ /CD4+)

11.1 +/- 0.7

13.8 +/- 1.0

**

# (CD44+ /CD4+)

8.1 +/- 1.0

14.4 +/- 1.6

**


# Only gated CD3+ cells were taken into account for these calculations

Graca et al. BMC Immunology 2006 7:9   doi:10.1186/1471-2172-7-9

Open Data