Table 1

FoxP3+CD4+CD25+ thymocytes in neonatal mice a

# Cells (103)

day 1

day2

day 3

day 4

day 5

day 6

day 8

Adult


Total Thymocyte

1,005 b +/-177

3,390 +/-410

6,210 +/-127

9,410 +/-2,107

32,600 +/-18,668

31,000 +/-12,021

57,700 +/-2,263

75,900 +/-12,304

CD4+CD8-

13 +/-1.9

117 +/-36.4

457 +/-44.5

350 +/-16.2

828 +/-526

732 +/-361

1,738 +/-256

5,606 +/-1,751

CD4+CD25+CD8-

0.1 (.82%)C +/-0.02

0.9 (.86%) +/-0.6

3.1 (.86%) +/-0.3

2.6 (.92%) +/-0.2

3.7 (.76%) +/-2.2

4.5 (.98%) +/-1.9

18.1 (.86%) +/-0.3

91.1 (2.2%) +/-27

Foxp3+CD4+CD25+CD8-

0

0

0.8 (21%)d +/-0.1

0.9 (37%) +/-0.1

1.6 (43%) +/-0.9

1.9 (43%) +/-0.7

10.8 (59%) +/-0.1

64.5 (71%) +/-17.9


a Total thymocytes from day 1–8 newborn or adult mice were stained with CD4, CD8, CD25 and anti-FoxP3 antibody and analyzed by FACS. Data is a summary of three independent analyses. b: Average cell number +/- standard deviations (SD). c: % CD25+ of CD4+CD8- thymocytes. d: % FoxP3+ of CD4+CD25+CD8- thymocytes.

Jiang et al. BMC Immunology 2006 7:6   doi:10.1186/1471-2172-7-6

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