Table 3

MBL2 genotypes and infections in 72 patients with ASCT during the 6 months of follow-up
AA AO/OO RR (95% CI) P-value*
Patients (%) Patients (%)
n = 53 n = 19
Types of Infection
  -Pneumonia 2 (3.8) 2 (10.5) 2.8(0.4-18.4) 0.28
  -Sepsis 22 (41.5) 9 (47.4) 1.1 (0.6-2.0) 0.66
  -VCI 6 (11.3) 2 (10.5) 0.9 (0.2-4.2) 1.00
  -UTI 5 (9.4) 3 (15.8) 1.7 (0.4-6.3) 0.43
Major infection 6 (11.3) 5 (26.3) 2.32 (0.80-6.74) 0.15
Gram-positive infections 14 (26.4) 9 (47.4) 1.8 (0.9-3.4) 0.09
  -S. epidermidis 9 (17) 7 (36.8) 2.2 (0.9-5.0) 0.11
  -S. aureus 1 (1.9) 0 (0) -- 1.00
  -Other
Gram-negative infections 19 (35.8) 6 (31.6) 0.9 (0.4-1.9) 0.74
Viral infections 1 (1.9) 1 (5.3) 2.8 (0.2-42.4) 0.46
  -CMV 0 (0) 1 (5.3) -- 0.26
Fungal infections 1 (1.9) 4 (21.1) 11.5 (1.3-93.7) 0.016
  -Candida 1(1.9) 2 (10.5) 5.6 (0.5-58.1) 0.17
  -Aspergillus 0 (0) 1 (5.3) -- 0.26
  -Mucor 0 (0) 1 (5.3) -- 0.26
Nº deaths 4 (7.5) 3 (15.8) 2.1 (0.5-8.5) 0.37
Cause of death
  -Infection 0 3 -- 0.05
  -Progression 3 0 --
  -Unknown (not infection) 1 0 --

*Two-tailed Chi-squared test or Fisher exact test as corresponding.

RR: risk ratio; CI: confidence interval.

VCI: Venous catheter infection; UTI: Urinary tract infection.

AA genotype: patients homozygous for wild-type structural allele (A).

AO/OO genotype: patients heterozygous or homozygous for the B, C or D alleles.

Moreto et al.

Moreto et al. BMC Immunology 2014 15:17   doi:10.1186/1471-2172-15-17

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