Additional file 6.

Figure S4. Log ratio of the expression levels of genes associated the mTECu-T-DMRs and mTECany2-T-DMRs. Relative expression levels of genes associated with mTECu-T-DMRs (upper) and mTECany2-T-DMRs (lower) in Aire−/− mTECs, Aire+/+ mTECs, liver and CD4+CD8+ thymocytes to Aire−/− mTECs. From left to right, the data sets represented the all probed genes and the T-DMRs, classified according to their relative distance to TSSs as −6 to +2.5 kb (whole window), -1 to +2.5 kb (proximal) and −6 to −1 kb (distal) regions. The vertical axis of the box-plot represents the values of gene expression levels of duplicated data sets relative to one microarray profile of Aire−/− mTECs. The numbers in the round brackets indicate independent gene expression profiles of each type of cell or tissues listed in Table S2. * indicates significant differences in relative expression levels where the p values of t-tests are less than −0.1. (PDF 128 kb)

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Wu et al. BMC Immunology 2012 13:58   doi:10.1186/1471-2172-13-58