Open Access Research article

Biodistribution and elimination kinetics of systemic Stx2 by the Stx2A and Stx2B subunit-specific human monoclonal antibodies in mice

Abhineet Sheoran1*, Kwang-il Jeong12, Jean Mukherjee1, Anthony Wiffin1, Pradeep Singh3 and Saul Tzipori1

Author Affiliations

1 Department of Biomedical Sciences, Cummings School of Veterinary Medicine, Tufts University, 200 Westboro Road Building 20, North Grafton, MA, USA

2 Vaccine Research Center, 401 North Middletown Road Pfizer, Pearl River, NY, 10965, USA

3 Department of Mathematics, Southeast Missouri State University, 401 North Middletown Road Pfizer, Cape Girardeau, MO, 63701, USA

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BMC Immunology 2012, 13:27  doi:10.1186/1471-2172-13-27

Published: 1 June 2012

Additional files

Additional file 1:

Table S1. Distribution of 125I-Stx2 in body fluids and tissues following 3 h, 1 day and 2 days of 125I-Stx2 injection.1

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