The biodistribution of 18F-FIAU radioactive counts in major organs and fluid specimens of mice. The animal model and the treatment are described in the figure 10 legend. Mice were euthanized after 140 min of injecting 18F-FIAU probe, and major organs and fluids were harvested. The radioactive counts were corrected for physical decay of 18F (half-life 110 min), and normalized with tissue weight. The intestine and stomach (insets) were calculated as percent injected dose for entire organ, because of the unavoidable problem related to the presence of variable amounts of food and fecal matter significantly altering the tissue weight from one animal to the other. * p < 0.005, # p < 0.05 versus control (mice injected with DCs transfected with vector plasmid DNA). Results shown here are mean (SEM) of three experiments with 6 mice in each group.
Vilekar et al. BMC Immunology 2010 11:60 doi:10.1186/1471-2172-11-60