The cytoplasmic tyrosine residues of the human IL-7Rα are not required for TSLP-dependent cell proliferation. TSLP-induced proliferation of Ba/F3 cells co-expressing the indicated receptors was examined as described in Figure 2D. The proliferative response to different doses of TSLP was assessed in Ba/F3 cells expressing the indicated receptors as described in Figure 2E. Statistically significance was calculated using Student's t-test (* indicates a significant difference with p-value < 0.01; **p-value < 0.05). (The growth of cells was examined in 3 independent sets of experiments and found to be similar. The results from one representative experiment are shown).
Zhong and Pandey BMC Immunology 2010 11:5 doi:10.1186/1471-2172-11-5