BMC Immunology

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Open Access Highly Access Research article

Peripheral blood T Regulatory cell counts may not predict transplant rejection

Yuchuan Huang1,2, Juan Shan1, Chuntao Zhang1, Jie Zhang1, Li Feng1, Shengfu Li1 and Youping Li1,3*

Author Affiliations

1 Key Laboratory of Transplant Engineering and Immunology, Ministry of Health, West China Hospital, Sichuan University, Chengdu China

2 Technology Research and Development Center, China Tobacco Chuanyu Industrial Corporation. Chengdu China

3 Chinese Cochrane Centre, Chinese Evidence-Based Medicine Centre. Chengdu China

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BMC Immunology 2010, 11:40 doi:10.1186/1471-2172-11-40

Published: 15 July 2010

Additional files

Additional file 1:

the histology of Foxp3 expression in spleens. We assessed the dynamic changes in the number of Foxp3+ Tregs in the spleens by immunohistochemistry. Tissue sections were stained using an anti-Foxp3 monoclonal antibody. Con group POD 1: 1st day after transplantation; POD 3: 3rd days after transplantation; POD6: 6th day after transplantation; 1 D group 1+1d: 1st day after RAPA treatment in 1D group; 1+3d: 3rd day after RAPA treatment in 1D group; 1+7d: 7th day after RAPA treatment in 1D group; 1+10d: 10th day after RAPA treatment in 1D group; 3D group 3+1d: 1st day after RAPA treatment in 3D group; 3+3d: 3rd day after RAPA treatment in 3D group; 3+7d: 7th day after RAPA treatment in 3D group; 3+11d: 11th day after RAPA treatment in 3D group.

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Additional file 2:

the histology of Foxp3 expression in lymph nodes (LN). We assessed the dynamic changes in the number of Foxp3+ Tregs in the lymph nodes(LN) by immunohistochemistry. Tissue sections were stained using an anti-Foxp3 monoclonal antibody. Con group POD 1: 1st day after transplantation; POD 3: 3rd days after transplantation; POD6: 6th day after transplantation; 1 D group 1+1d: 1st day after RAPA treatment in 1D group; 1+3d: 3rd day after RAPA treatment in 1D group; 1+7d: 7th day after RAPA treatment in 1D group; 1+10d: 10th day after RAPA treatment in 1D group; 3D group 3+1d: 1st day after RAPA treatment in 3D group; 3+3d: 3rd day after RAPA treatment in 3D group; 3+7d: 7th day after RAPA treatment in 3D group; 3+11d: 11th day after RAPA treatment in 3D group.

Format: TIFF Size: 1.1MB Download file

Open Data