Research article
Changes in colon gene expression associated with increased colon inflammation in interleukin-10 gene-deficient mice inoculated with Enterococcus species
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* Corresponding author: Matthew PG Barnett matthew.barnett@agresearch.co.nz
1 Food, Metabolism & Microbiology Section, AgResearch Grasslands, Tennent Drive, Palmerston North 4442, New Zealand
2 Food & Textiles Group, AgResearch Grasslands, Tennent Drive, Palmerston North 4442, New Zealand
3 Riddet Institute, Massey University, Palmerston North, NZ
4 Faculty of Medical and Health Sciences, The University of Auckland, 85 Park Road, Grafton, Auckland 1023, New Zealand
5 Plant & Food Research, Ruakura Research Centre, East Street, Hamilton 3214, New Zealand
6 Institute of Food, Nutrition & Human Health, Massey University, Tennent Drive, Palmerston North 4442, New Zealand
7 Plant & Food Research, Batchelar Road, Palmerston North 4442, New Zealand
8 Dairy Science & Technology, AgResearch Ruakura, East Street, Hamilton 3214, New Zealand
BMC Immunology 2010, 11:39 doi:10.1186/1471-2172-11-39
Published: 15 July 2010Additional files
Additional file 1:
Pathways with genes differentially expressed in Il10-/- mice in response to the 1) SPF, 2) C, 3) EF, 4) CIF and 5) EF·CIF treatments when compared with similarly-inoculated C57 mice. Fold-change and P-values for genes in the top 10 most significant canonical pathways as identified by Ingenuity Pathways Analysis (using Fischer's exact test, as shown in Table 5 within the main text). For those comparisons where there was a significant difference between Il10-/- and C57 mice, the text is shown in italics.
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