Table 1 |
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|
24 h Survival status in BoNT/B-mouse neutralization assaya. |
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|
Vaccination Groupb |
Sera Titerc |
%Survivald |
p-valuee |
|
|
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|
Naïve |
0 |
0 |
- |
|
Hcβtre/B + CT |
19.5 ± 0.5 |
100 |
< 0.05 |
|
|
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|
Hcβtre-Ad2F + CT |
19.8 ± 0.2 |
100 |
< 0.05 |
|
|
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|
a Pooled sera from nasally vaccinated or naive mice incubated for 1 h with 2.0 LD50 of BoNT/B in PBS-0.2% gelatin and then injected into naive mice. b Source of sera used. c Endpoint titer for Hc/B in pooled sera (10 mice/group). d Survival of BoNT/B-challenged mice after 24 h. e p-value determined by Kaplan-Meier method. |
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|
Clapp et al. BMC Immunology 2010 11:36 doi:10.1186/1471-2172-11-36 |
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