The effects of CFA on the IL-4 production induced by Sj infection. Splenocytes from mice of uninfected (CTRL), 2 weeks of Sj infection, 7 to 10 weeks of Sj infection, 15 weeks of Sj infection, CIA, ESCIA (total 10 weeks of Sj infection), ASCIA (total 15 weeks of Sj infection) were stimulated by anti-CD3 and anti-CD28 antibodies for 72 hrs. The IL-4 contents in the supernatants were measured by ELISA. Shown are samples from individual mouse combined from two or three separately performed experiments. Asterisks* and ** represented P < 0.05 and P < 0.01 respectively by one-way ANOVA with Bonferroni multiple comparison test.
He et al. BMC Immunology 2010 11:28 doi:10.1186/1471-2172-11-28